126 transactions by 16 insiders, from October 10, 2025 to September 17, 2026.
People inside the company. What they do with their own shares is the reason this data exists.
| Insider | Trades | Planned | Bought | Sold |
|---|---|---|---|---|
| Bruce BoothDir | 41 | 40/41 | — | $18.2M |
| Michael CloonanCEO | 26 | 21/26 | — | $4.4M |
| Peter A. ThompsonDir | 14 | 13/14 | — | $49.3M |
| ORBIMED ADVISORS LLCDir | 13 | 13/13 | — | $49.3M |
| Jennifer FitzpatrickOfficer | 11 | 6/11 | — | $794K |
| Elena RidloffCFO | 5 | — | — | — |
| Charlotte McKeeCMO | 5 | — | — | — |
| RA CAPITAL MANAGEMENT, L.P.Dir | 3 | — | — | $21.8M |
| Paul J. ClancyDir | 1 | — | — | — |
| Joanne L. VineyDir | 1 | — | — | — |
| Harold Edward FlemingDir | 1 | — | — | — |
| Marcella K. RuddyDir | 1 | — | — | — |
| Caroline Stark BeerChief | 1 | — | — | — |
| Laurie StelzerDir | 1 | — | — | — |
| Joshua ResnickDir | 1 | — | — | — |
Holders above 10%, often funds. They file the same form, but they trade for portfolio reasons, not because of what they know.
| Insider | Trades | Planned | Bought | Sold |
|---|---|---|---|---|
| TPG GP A, LLC10% | 1 | — | — | $10.0M |
126 in total, newest filings first.
| Insider | Date | Code | Shares | Price | Value |
|---|---|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P.DirJOINT | Sep 17 | S | 33,800 | $7.46 | $252K |
| RA CAPITAL MANAGEMENT, L.P.DirJOINT | Sep 17 | S | 3,415,011 | $6.32 | $21.6M |
| Elena RidloffCFODERIV | Sep 17 | D | 165,440 | $0.00 | —? |
| Elena RidloffCFODERIV | Sep 17 | A | 165,440 | $0.00 | —? |
| Elena RidloffCFO | Sep 17 | A | 47,268 | $0.00 | — |
| Elena RidloffCFO | Sep 17 | A | 47,269 | $0.00 | — |
| Charlotte McKeeCMODERIV | Sep 17 | D | 155,700 | $0.00 | —? |
| Charlotte McKeeCMODERIV | Sep 17 | A | 155,700 | $0.00 | —? |
| Charlotte McKeeCMO | Sep 17 | A | 50,000 | $0.00 | — |
| Charlotte McKeeCMO | Sep 17 | A | 50,000 | $0.00 | — |
| Jennifer FitzpatrickOfficerDERIV | Sep 17 | D | 103,140 | $0.00 | —? |
| Jennifer FitzpatrickOfficerDERIV | Sep 17 | A | 103,140 | $0.00 | —? |
| Jennifer FitzpatrickOfficer | Sep 17 | A | 28,132 | $0.00 | — |
| Jennifer FitzpatrickOfficer | Sep 17 | A | 28,133 | $0.00 | — |
| Michael CloonanCEODERIV | Sep 17 | D | 436,100 | $0.00 | —? |
| Michael CloonanCEODERIV | Sep 17 | A | 436,100 | $0.00 | —? |
| Michael CloonanCEO | Sep 17 | A | 109,025 | $0.00 | — |
| Michael CloonanCEO | Sep 17 | A | 109,025 | $0.00 | — |
| Peter A. ThompsonDir | Jul 7 | SPLAN | 85,918 | $44.86 | $3.9M |
| ORBIMED ADVISORS LLCDirJOINT | Jul 7 | SPLAN | 85,918 | $44.86 | $3.9M |
| Jennifer FitzpatrickGCDERIV | Jul 6 | MPLAN | 10,250 | $0.00 | —? |
| Jennifer FitzpatrickGC | Jul 6 | SPLAN | 10,250 | $43.60 | $447K |
| Jennifer FitzpatrickGC | Jul 6 | MPLAN | 10,250 | $6.11 | $63K |
| Peter A. ThompsonDir | Jun 30 | SPLAN | 115,844 | $45.50 | $5.3M |
| ORBIMED ADVISORS LLCDirJOINT | Jun 30 | SPLAN | 115,844 | $45.50 | $5.3M |
| Joanne L. VineyDirDERIV | Jun 17 | A | 17,340 | $0.00 | —? |
| Laurie StelzerDirDERIV | Jun 17 | A | 17,340 | $0.00 | —? |
| Peter A. ThompsonDirDERIV | Jun 17 | A | 17,340 | $0.00 | —? |
| Marcella K. RuddyDirDERIV | Jun 17 | A | 17,340 | $0.00 | —? |
| Joshua ResnickDirDERIV | Jun 17 | A | 17,340 | $0.00 | —? |
| RA CAPITAL MANAGEMENT, L.P.DirDERIVJOINT | Jun 17 | A | 17,340 | $0.00 | —? |
| Harold Edward FlemingDirDERIV | Jun 17 | A | 17,340 | $0.00 | —? |
| Paul J. ClancyDirDERIV | Jun 17 | A | 17,340 | $0.00 | —? |
| Bruce BoothDirDERIV | Jun 17 | A | 17,340 | $0.00 | —? |
| Peter A. ThompsonDir | May 27 | SPLAN | 101 | $44.49 | $4K |
| ORBIMED ADVISORS LLCDirJOINT | May 27 | SPLAN | 101 | $44.49 | $4K |
| Peter A. ThompsonDir | May 11 | SPLAN | 184,639 | $46.22 | $8.5M |
| Peter A. ThompsonDir | May 8 | SPLAN | 59,767 | $44.58 | $2.7M |
| Peter A. ThompsonDir | May 7 | SPLAN | 48,546 | $44.61 | $2.2M |
| ORBIMED ADVISORS LLCDirJOINT | May 11 | SPLAN | 184,639 | $46.22 | $8.5M |
| ORBIMED ADVISORS LLCDirJOINT | May 8 | SPLAN | 59,767 | $44.58 | $2.7M |
| ORBIMED ADVISORS LLCDirJOINT | May 7 | SPLAN | 48,546 | $44.61 | $2.2M |
| Peter A. ThompsonDir | Apr 18 | SPLAN | 2,948 | $44.52 | $131K |
| Peter A. ThompsonDir | Apr 17 | SPLAN | 52,397 | $44.68 | $2.3M |
| ORBIMED ADVISORS LLCDirJOINT | Apr 18 | SPLAN | 2,948 | $44.52 | $131K |
| ORBIMED ADVISORS LLCDirJOINT | Apr 17 | SPLAN | 52,397 | $44.68 | $2.3M |
| Peter A. ThompsonDir | Apr 16 | SPLAN | 226,906 | $45.34 | $10.3M |
| Peter A. ThompsonDir | Apr 15 | SPLAN | 235,863 | $44.64 | $10.5M |
| Peter A. ThompsonDir | Apr 14 | SPLAN | 47,814 | $44.51 | $2.1M |
| ORBIMED ADVISORS LLCDirJOINT | Apr 16 | SPLAN | 226,906 | $45.34 | $10.3M |
| ORBIMED ADVISORS LLCDirJOINT | Apr 15 | SPLAN | 235,863 | $44.64 | $10.5M |
| ORBIMED ADVISORS LLCDirJOINT | Apr 14 | SPLAN | 47,814 | $44.51 | $2.1M |
| Jennifer FitzpatrickGCDERIV | Mar 5 | MPLAN | 10,250 | $0.00 | —? |
| Jennifer FitzpatrickGC | Mar 5 | SPLAN | 10,250 | $33.86 | $347K |
| Jennifer FitzpatrickGC | Mar 5 | MPLAN | 10,250 | $6.11 | $63K |
| Peter A. ThompsonDir | Feb 3 | SPLAN | 29,063 | $44.58 | $1.3M |
| Peter A. ThompsonDir | Feb 2 | SPLAN | 1,890 | $44.57 | $84K |
| ORBIMED ADVISORS LLCDirJOINT | Feb 3 | SPLAN | 29,063 | $44.58 | $1.3M |
| ORBIMED ADVISORS LLCDirJOINT | Feb 2 | SPLAN | 1,890 | $44.57 | $84K |
| TPG GP A, LLC10%JOINT | Jan 22 | S | 250,000 | $40.00 | $10.0M |
| Elena RidloffCFODERIV | Jan 2 | A | 165,440 | $0.00 | —? |
| Charlotte McKeeCMODERIV | Jan 2 | A | 155,700 | $0.00 | —? |
| Jennifer FitzpatrickGCDERIV | Jan 2 | A | 103,140 | $0.00 | —? |
| Michael CloonanCEODERIV | Jan 2 | A | 436,100 | $0.00 | —? |
| Caroline Stark BeerChiefDERIV | Jan 2 | A | 139,340 | $0.00 | —? |
| Michael CloonanCEODERIV | Oct 21 | MPLAN | 33,532 | $0.00 | —? |
| Michael CloonanCEODERIV | Oct 21 | MPLAN | 22,895 | $0.00 | —? |
| Michael CloonanCEODERIV | Oct 21 | MPLAN | 30,049 | $0.00 | —? |
| Michael CloonanCEODERIV | Oct 21 | MPLAN | 13,324 | $0.00 | —? |
| Michael CloonanCEO | Oct 21 | SPLAN | 33,532 | $37.31 | $1.3M |
| Michael CloonanCEO | Oct 21 | MPLAN | 33,532 | $6.11 | $205K |
| Michael CloonanCEO | Oct 21 | SPLAN | 22,895 | $36.60 | $838K |
| Michael CloonanCEO | Oct 21 | MPLAN | 22,895 | $6.11 | $140K |
| Michael CloonanCEO | Oct 21 | SPLAN | 30,049 | $35.63 | $1.1M |
| Michael CloonanCEO | Oct 21 | MPLAN | 30,049 | $6.11 | $184K |
| Michael CloonanCEO | Oct 21 | SPLAN | 13,324 | $34.44 | $459K |
| Michael CloonanCEO | Oct 21 | MPLAN | 13,324 | $6.11 | $81K |
| Bruce BoothDir | Oct 21 | SPLAN | 17 | $36.42 | $619 |
| Bruce BoothDir | Oct 21 | SPLAN | 83 | $36.42 | $3K |
| Bruce BoothDir | Oct 21 | SPLAN | 5,316 | $35.69 | $190K |
| Bruce BoothDir | Oct 21 | SPLAN | 25,327 | $35.69 | $904K |
| Bruce BoothDir | Oct 21 | SPLAN | 1,210 | $34.91 | $42K |
| Bruce BoothDir | Oct 21 | SPLAN | 5,763 | $34.91 | $201K |
| Bruce BoothDir | Oct 21 | SPLAN | 4,187 | $33.87 | $142K |
| Bruce BoothDir | Oct 21 | SPLAN | 19,948 | $33.87 | $676K |
| Bruce BoothDir | Oct 21 | SPLAN | 4,688 | $32.69 | $153K |
| Bruce BoothDir | Oct 21 | SPLAN | 22,339 | $32.69 | $730K |
| Bruce BoothDir | Oct 20 | SPLAN | 5,412 | $32.33 | $175K |
| Bruce BoothDir | Oct 20 | SPLAN | 25,788 | $32.33 | $834K |
| Bruce BoothDir | Oct 20 | SPLAN | 4,300 | $31.79 | $137K |
| Bruce BoothDir | Oct 20 | SPLAN | 20,485 | $31.79 | $651K |
| Bruce BoothDir | Oct 17 | SPLAN | 52 | $33.47 | $2K |
| Bruce BoothDir | Oct 17 | SPLAN | 248 | $33.47 | $8K |
| Bruce BoothDir | Oct 17 | SPLAN | 4,503 | $32.71 | $147K |
| Bruce BoothDir | Oct 17 | SPLAN | 21,451 | $32.71 | $702K |
| Bruce BoothDir | Oct 17 | SPLAN | 6,049 | $32.10 | $194K |
| Bruce BoothDir | Oct 17 | SPLAN | 28,821 | $32.10 | $925K |
| Bruce BoothDir | Oct 16 | SPLAN | 2,705 | $33.38 | $90K |
| Bruce BoothDir | Oct 16 | SPLAN | 12,888 | $33.38 | $430K |
| Bruce BoothDir | Oct 16 | SPLAN | 15,384 | $32.84 | $505K |
| Bruce BoothDir | Oct 16 | SPLAN | 73,296 | $32.84 | $2.4M |
| Bruce BoothDir | Oct 16 | SPLAN | 9,470 | $31.69 | $300K |
| Bruce BoothDir | Oct 16 | SPLAN | 45,117 | $31.69 | $1.4M |
| Bruce BoothDir | Oct 16 | SPLAN | 1,804 | $30.15 | $54K |
| Bruce BoothDir | Oct 16 | SPLAN | 8,596 | $30.15 | $259K |
| Michael CloonanCEODERIV | Oct 16 | MPLAN | 200 | $0.00 | —? |
| Michael CloonanCEODERIV | Oct 16 | MPLAN | 10,225 | $0.00 | —? |
| Michael CloonanCEODERIV | Oct 15 | MPLAN | 14,775 | $0.00 | —? |
| Michael CloonanCEO | Oct 16 | SPLAN | 200 | $34.00 | $7K |
| Michael CloonanCEO | Oct 16 | MPLAN | 200 | $6.11 | $1K |
| Michael CloonanCEO | Oct 16 | SPLAN | 10,225 | $31.46 | $322K |
| Michael CloonanCEO | Oct 16 | MPLAN | 10,225 | $6.11 | $62K |
| Michael CloonanCEO | Oct 15 | SPLAN | 14,775 | $31.11 | $460K |
| Michael CloonanCEO | Oct 15 | MPLAN | 14,775 | $6.11 | $90K |
| Bruce BoothDir | Oct 15 | SPLAN | 6,303 | $31.12 | $196K |
| Bruce BoothDir | Oct 15 | SPLAN | 30,032 | $31.12 | $935K |
| Bruce BoothDir | Oct 15 | SPLAN | 13,795 | $30.37 | $419K |
| Bruce BoothDir | Oct 15 | SPLAN | 65,726 | $30.37 | $2.0M |
| Bruce BoothDir | Oct 14 | SPLAN | 105 | $29.95 | $3K |
| Bruce BoothDir | Oct 14 | SPLAN | 501 | $29.95 | $15K |
| Bruce BoothDir | Oct 13 | SPLAN | 857 | $31.03 | $27K |
| Bruce BoothDir | Oct 13 | SPLAN | 4,082 | $31.03 | $127K |
| Bruce BoothDir | Oct 13 | SPLAN | 9,245 | $30.32 | $280K |
| Bruce BoothDir | Oct 13 | SPLAN | 44,048 | $30.32 | $1.3M |
| Bruce BoothDir | Oct 10 | SPLAN | 3,511 | $29.98 | $105K |
| Bruce BoothDir | Oct 10 | SPLAN | 16,727 | $29.98 | $501K |