248 transactions by 14 insiders, from November 6, 2025 to August 17, 2026.
People inside the company. What they do with their own shares is the reason this data exists.
| Insider | Trades | Planned | Bought | Sold |
|---|---|---|---|---|
| William LewisCEO | 114 | 106/114 | — | $28.8M |
| Martina Flammer M.D.CMO | 54 | 54/54 | — | $15.6M |
| Roger AdsettCOO | 20 | 5/20 | — | $48.3M |
| Michael Alexander SmithGC | 20 | 12/20 | — | $9.0M |
| Orlov S. Nicole SchaefferChief | 9 | 9/9 | — | $15.3M |
| Sara BonsteinCFO | 9 | — | — | $2.1M |
| Melvin Sharoky M.D.Dir | 8 | — | — | $638K |
| David R. BrennanDir | 4 | — | — | — |
| Elizabeth M. AndersonDir | 3 | — | — | $3.0M |
| David W. J. McGirrDir | 2 | — | — | — |
| Samuele ButeraSVP | 2 | — | — | — |
| Clarissa DesjardinsDir | 1 | — | — | — |
| Leo LeeDir | 1 | — | — | — |
| Carol SchaferDir | 1 | — | — | — |
248 in total, newest filings first.
| Insider | Date | Code | Shares | Price | Value |
|---|---|---|---|---|---|
| Melvin Sharoky M.D.Dir | Aug 17 | S | 5,000 | $127.53 | $638K |
| Roger AdsettCOODERIV | Aug 10 | M | 80,970 | $0.00 | —? |
| Roger AdsettCOODERIV | Aug 10 | M | 76,600 | $0.00 | —? |
| Roger AdsettCOODERIV | Aug 10 | M | 82,280 | $0.00 | —? |
| Roger AdsettCOO | Aug 10 | S | 239,850 | $133.27 | $32.0M |
| Roger AdsettCOO | Aug 10 | M | 80,970 | $30.46 | $2.5M |
| Roger AdsettCOO | Aug 10 | M | 76,600 | $17.16 | $1.3M |
| Roger AdsettCOO | Aug 10 | M | 82,280 | $13.67 | $1.1M |
| Martina Flammer M.D.CMODERIV | Aug 6 | MPLAN | 8,895 | $0.00 | —? |
| Martina Flammer M.D.CMODERIV | Aug 6 | MPLAN | 18,278 | $0.00 | —? |
| Martina Flammer M.D.CMO | Aug 6 | SPLAN | 18,278 | $129.40 | $2.4M |
| Martina Flammer M.D.CMO | Aug 6 | SPLAN | 8,895 | $127.00 | $1.1M |
| Martina Flammer M.D.CMO | Aug 6 | MPLAN | 8,895 | $25.83 | $230K |
| Martina Flammer M.D.CMO | Aug 6 | MPLAN | 18,278 | $18.95 | $346K |
| William LewisCEODERIV | Jul 23 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | Jul 23 | MPLAN | 6,260 | $0.00 | —? |
| William LewisCEO | Jul 23 | SPLAN | 5,872 | $106.43 | $625K |
| William LewisCEO | Jul 23 | SPLAN | 4,828 | $105.62 | $510K |
| William LewisCEO | Jul 23 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | Jul 23 | MPLAN | 6,260 | $30.46 | $191K |
| William LewisCEODERIV | Jul 9 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | Jul 9 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEO | Jul 9 | SPLAN | 3,359 | $118.52 | $398K |
| William LewisCEO | Jul 9 | SPLAN | 2,335 | $117.62 | $275K |
| William LewisCEO | Jul 9 | SPLAN | 5,005 | $116.55 | $583K |
| William LewisCEO | Jul 9 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | Jul 9 | MPLAN | 6,259 | $30.46 | $191K |
| Martina Flammer M.D.CMODERIV | Jul 6 | MPLAN | 4,357 | $0.00 | —? |
| Martina Flammer M.D.CMODERIV | Jul 6 | MPLAN | 7,945 | $0.00 | —? |
| Martina Flammer M.D.CMO | Jul 6 | SPLAN | 7,448 | $110.60 | $824K |
| Martina Flammer M.D.CMO | Jul 6 | SPLAN | 4,854 | $109.02 | $529K |
| Martina Flammer M.D.CMO | Jul 6 | MPLAN | 4,357 | $19.74 | $86K |
| Martina Flammer M.D.CMO | Jul 6 | MPLAN | 7,945 | $29.13 | $231K |
| William LewisCEODERIV | Jun 25 | MPLAN | 8,880 | $0.00 | —? |
| William LewisCEODERIV | Jun 25 | MPLAN | 12,518 | $0.00 | —? |
| William LewisCEO | Jun 25 | SPLAN | 1,292 | $106.27 | $137K |
| William LewisCEO | Jun 25 | SPLAN | 2,456 | $105.27 | $259K |
| William LewisCEO | Jun 25 | SPLAN | 3,723 | $104.28 | $388K |
| William LewisCEO | Jun 25 | SPLAN | 1,836 | $103.10 | $189K |
| William LewisCEO | Jun 25 | SPLAN | 12,091 | $102.34 | $1.2M |
| William LewisCEO | Jun 25 | MPLAN | 8,880 | $17.16 | $152K |
| William LewisCEO | Jun 25 | MPLAN | 12,518 | $30.46 | $381K |
| Michael Alexander SmithGC | Jun 22 | SPLAN | 1,806 | $95.82 | $173K |
| Samuele ButeraSVPDERIV | Jun 23 | A | 12,570 | $0.00 | —? |
| Samuele ButeraSVP | Jun 23 | A | 7,342 | — | — |
| William LewisCEO | Jun 8 | SPLAN | 6,515 | $94.03 | $613K |
| Michael Alexander SmithGC | Jun 3 | S | 2,159 | $102.27 | $221K |
| William LewisCEO | Jun 3 | S | 7,605 | $102.27 | $778K |
| Martina Flammer M.D.CMO | Jun 5 | SPLAN | 1,858 | $103.78 | $193K |
| Martina Flammer M.D.CMO | Jun 3 | SPLAN | 2,566 | $102.27 | $262K |
| Sara BonsteinCFO | Jun 3 | S | 2,404 | $102.27 | $246K |
| Roger AdsettCOO | Jun 3 | S | 2,370 | $102.27 | $242K |
| Michael Alexander SmithGC | May 22 | SPLAN | 6,149 | $108.47 | $667K |
| William LewisCEODERIV | May 18 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | May 18 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEO | May 18 | SPLAN | 7,975 | $106.97 | $853K |
| William LewisCEO | May 18 | SPLAN | 11,836 | $106.39 | $1.3M |
| William LewisCEO | May 18 | SPLAN | 5,753 | $105.32 | $606K |
| William LewisCEO | May 18 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | May 18 | MPLAN | 6,259 | $30.46 | $191K |
| Michael Alexander SmithGC | May 13 | S | 4,109 | $116.18 | $477K |
| Leo LeeDir | May 13 | A | 3,305 | — | — |
| William LewisCEO | May 13 | S | 13,283 | $116.18 | $1.5M |
| Carol SchaferDir | May 13 | A | 3,305 | — | — |
| Melvin Sharoky M.D.Dir | May 13 | A | 3,305 | — | — |
| Martina Flammer M.D.CMO | May 14 | SPLAN | 10,479 | $117.54 | $1.2M |
| Martina Flammer M.D.CMO | May 13 | SPLAN | 3,384 | $116.18 | $393K |
| Martina Flammer M.D.CMO | May 13 | SPLAN | 4,470 | $112.76 | $504K |
| Clarissa DesjardinsDir | May 13 | A | 3,305 | — | — |
| David R. BrennanDir | May 13 | A | 3,305 | — | — |
| Sara BonsteinCFO | May 13 | S | 8,272 | $116.18 | $961K |
| Roger AdsettCOO | May 13 | S | 5,837 | $116.18 | $678K |
| Elizabeth M. AndersonDir | May 13 | A | 3,305 | — | — |
| Martina Flammer M.D.CMODERIV | May 11 | MPLAN | 12,949 | $0.00 | —? |
| Martina Flammer M.D.CMO | May 11 | SPLAN | 830 | $101.18 | $84K |
| Martina Flammer M.D.CMO | May 11 | SPLAN | 12,119 | $100.35 | $1.2M |
| Martina Flammer M.D.CMO | May 11 | MPLAN | 12,949 | $17.07 | $221K |
| William LewisCEODERIV | May 4 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | May 4 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEO | May 4 | SPLAN | 381 | $139.60 | $53K |
| William LewisCEO | May 4 | SPLAN | 1,247 | $139.09 | $173K |
| William LewisCEO | May 4 | SPLAN | 2,721 | $137.86 | $375K |
| William LewisCEO | May 4 | SPLAN | 5,318 | $137.01 | $729K |
| William LewisCEO | May 4 | SPLAN | 599 | $135.18 | $81K |
| William LewisCEO | May 4 | SPLAN | 433 | $134.18 | $58K |
| William LewisCEO | May 4 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | May 4 | MPLAN | 6,259 | $30.46 | $191K |
| William LewisCEODERIV | Apr 16 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | Apr 16 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEO | Apr 16 | SPLAN | 825 | $145.79 | $120K |
| William LewisCEO | Apr 16 | SPLAN | 2,255 | $144.66 | $326K |
| William LewisCEO | Apr 16 | SPLAN | 5,373 | $143.81 | $773K |
| William LewisCEO | Apr 16 | SPLAN | 2,246 | $142.99 | $321K |
| William LewisCEO | Apr 16 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | Apr 16 | MPLAN | 6,259 | $30.46 | $191K |
| William LewisCEODERIV | Apr 6 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | Apr 6 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEO | Apr 6 | SPLAN | 1,434 | $164.01 | $235K |
| William LewisCEO | Apr 6 | SPLAN | 8,478 | $163.23 | $1.4M |
| William LewisCEO | Apr 6 | SPLAN | 787 | $161.73 | $127K |
| William LewisCEO | Apr 6 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | Apr 6 | MPLAN | 6,259 | $30.46 | $191K |
| Roger AdsettCOODERIV | Apr 1 | MPLAN | 88,060 | $0.00 | —? |
| Roger AdsettCOO | Apr 1 | SPLAN | 62,344 | $164.95 | $10.3M |
| Roger AdsettCOO | Apr 1 | SPLAN | 19,001 | $164.11 | $3.1M |
| Roger AdsettCOO | Apr 1 | SPLAN | 6,715 | $163.18 | $1.1M |
| Roger AdsettCOO | Apr 1 | MPLAN | 88,060 | $14.56 | $1.3M |
| Michael Alexander SmithGCDERIV | Mar 30 | MPLAN | 13,989 | $0.00 | —? |
| Michael Alexander SmithGCDERIV | Mar 30 | MPLAN | 5,649 | $0.00 | —? |
| Michael Alexander SmithGC | Mar 30 | SPLAN | 19,638 | $150.98 | $3.0M |
| Michael Alexander SmithGC | Mar 30 | MPLAN | 13,989 | $27.89 | $390K |
| Michael Alexander SmithGC | Mar 30 | MPLAN | 5,649 | $17.07 | $96K |
| William LewisCEODERIV | Mar 19 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | Mar 19 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEO | Mar 19 | SPLAN | 4,533 | $144.11 | $653K |
| William LewisCEO | Mar 19 | SPLAN | 4,537 | $143.42 | $651K |
| William LewisCEO | Mar 19 | SPLAN | 1,629 | $142.17 | $232K |
| William LewisCEO | Mar 19 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | Mar 19 | MPLAN | 6,259 | $30.46 | $191K |
| William LewisCEODERIV | Mar 5 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | Mar 5 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEO | Mar 5 | SPLAN | 2,128 | $147.54 | $314K |
| William LewisCEO | Mar 5 | SPLAN | 3,899 | $146.66 | $572K |
| William LewisCEO | Mar 5 | SPLAN | 2,589 | $145.27 | $376K |
| William LewisCEO | Mar 5 | SPLAN | 2,083 | $144.23 | $300K |
| William LewisCEO | Mar 5 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | Mar 5 | MPLAN | 6,259 | $30.46 | $191K |
| Melvin Sharoky M.D.Dir | Mar 3 | G | 100 | $0.00 | — |
| Melvin Sharoky M.D.Dir | Feb 25 | G | 243 | $0.00 | — |
| Melvin Sharoky M.D.Dir | Feb 25 | G | 243 | $0.00 | — |
| Melvin Sharoky M.D.Dir | Feb 25 | G | 243 | $0.00 | — |
| Melvin Sharoky M.D.Dir | Feb 25 | G | 243 | $0.00 | — |
| Melvin Sharoky M.D.Dir | Feb 25 | G | 1,072 | $0.00 | — |
| Michael Alexander SmithGCDERIV | Feb 24 | MPLAN | 20,248 | $0.00 | —? |
| Michael Alexander SmithGC | Feb 24 | SPLAN | 15,771 | $156.53 | $2.5M |
| Michael Alexander SmithGC | Feb 24 | SPLAN | 4,151 | $155.06 | $644K |
| Michael Alexander SmithGC | Feb 24 | SPLAN | 4,852 | $153.93 | $747K |
| Michael Alexander SmithGC | Feb 24 | MPLAN | 20,248 | $17.07 | $346K |
| David R. BrennanDir | Feb 23 | G | 6,000 | $0.00 | — |
| William LewisCEODERIV | Feb 19 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | Feb 19 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEO | Feb 19 | SPLAN | 1,030 | $153.38 | $158K |
| William LewisCEO | Feb 19 | SPLAN | 2,377 | $151.92 | $361K |
| William LewisCEO | Feb 19 | SPLAN | 3,413 | $151.12 | $516K |
| William LewisCEO | Feb 19 | SPLAN | 1,891 | $150.10 | $284K |
| William LewisCEO | Feb 19 | SPLAN | 1,988 | $149.17 | $297K |
| William LewisCEO | Feb 19 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | Feb 19 | MPLAN | 6,259 | $30.46 | $191K |
| William LewisCEODERIV | Feb 9 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEODERIV | Feb 9 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEO | Feb 9 | SPLAN | 1,287 | $148.83 | $192K |
| William LewisCEO | Feb 9 | SPLAN | 7,221 | $148.02 | $1.1M |
| William LewisCEO | Feb 9 | SPLAN | 4,888 | $147.17 | $719K |
| William LewisCEO | Feb 9 | MPLAN | 6,259 | $30.46 | $191K |
| William LewisCEO | Feb 9 | MPLAN | 4,440 | $17.16 | $76K |
| David W. J. McGirrDir | Feb 9 | G | 53,400 | $0.00 | — |
| David W. J. McGirrDir | Feb 9 | G | 53,400 | $0.00 | — |
| Martina Flammer M.D.CMO | Feb 5 | SPLAN | 869 | $152.44 | $132K |
| Michael Alexander SmithGC | Feb 3 | S | 640 | $156.27 | $100K |
| William LewisCEO | Feb 3 | S | 3,009 | $156.34 | $470K |
| Martina Flammer M.D.CMODERIV | Feb 2 | MPLAN | 7,982 | $0.00 | —? |
| Martina Flammer M.D.CMO | Feb 3 | SPLAN | 795 | $155.77 | $124K |
| Martina Flammer M.D.CMO | Feb 2 | SPLAN | 100 | $156.86 | $16K |
| Martina Flammer M.D.CMO | Feb 2 | SPLAN | 3,042 | $155.46 | $473K |
| Martina Flammer M.D.CMO | Feb 2 | SPLAN | 3,349 | $154.56 | $518K |
| Martina Flammer M.D.CMO | Feb 2 | SPLAN | 928 | $153.16 | $142K |
| Martina Flammer M.D.CMO | Feb 2 | SPLAN | 563 | $152.06 | $86K |
| Martina Flammer M.D.CMO | Feb 2 | MPLAN | 7,982 | $65.72 | $525K |
| Sara BonsteinCFO | Feb 3 | S | 748 | $156.34 | $117K |
| Roger AdsettCOO | Feb 3 | S | 791 | $156.17 | $124K |
| William LewisCEODERIV | Jan 20 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | Jan 20 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEO | Jan 20 | SPLAN | 254 | $160.70 | $41K |
| William LewisCEO | Jan 20 | SPLAN | 2,229 | $159.85 | $356K |
| William LewisCEO | Jan 20 | SPLAN | 5,967 | $158.99 | $949K |
| William LewisCEO | Jan 20 | SPLAN | 1,243 | $158.37 | $197K |
| William LewisCEO | Jan 20 | SPLAN | 1,006 | $156.80 | $158K |
| William LewisCEO | Jan 20 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | Jan 20 | MPLAN | 6,259 | $30.46 | $191K |
| William LewisCEODERIV | Jan 12 | MPLAN | 4,440 | $0.00 | —? |
| William LewisCEODERIV | Jan 12 | MPLAN | 6,259 | $0.00 | —? |
| William LewisCEO | Jan 12 | SPLAN | 315 | $174.86 | $55K |
| William LewisCEO | Jan 12 | SPLAN | 297 | $172.36 | $51K |
| William LewisCEO | Jan 12 | SPLAN | 297 | $171.31 | $51K |
| William LewisCEO | Jan 12 | SPLAN | 160 | $170.24 | $27K |
| William LewisCEO | Jan 12 | SPLAN | 6,996 | $169.57 | $1.2M |
| William LewisCEO | Jan 12 | SPLAN | 7,176 | $168.63 | $1.2M |
| William LewisCEO | Jan 12 | SPLAN | 3,974 | $167.73 | $667K |
| William LewisCEO | Jan 12 | MPLAN | 4,440 | $17.16 | $76K |
| William LewisCEO | Jan 12 | MPLAN | 6,259 | $30.46 | $191K |
| Martina Flammer M.D.CMO | Jan 9 | SPLAN | 1,887 | $186.19 | $351K |
| Michael Alexander SmithGC | Jan 8 | S | 1,053 | $174.17 | $183K |
| Michael Alexander SmithGC | Jan 7 | S | 709 | $175.07 | $124K |
| Michael Alexander SmithGC | Jan 6 | S | 1,396 | $173.33 | $242K |
| William LewisCEO | Jan 8 | S | 3,223 | $174.17 | $561K |
| William LewisCEO | Jan 7 | S | 2,357 | $175.07 | $413K |
| William LewisCEO | Jan 6 | S | 4,096 | $173.33 | $710K |
| Martina Flammer M.D.CMODERIV | Jan 6 | MPLAN | 8,570 | $0.00 | —? |
| Martina Flammer M.D.CMO | Jan 8 | SPLAN | 3,251 | $174.17 | $566K |
| Martina Flammer M.D.CMO | Jan 8 | SPLAN | 1,660 | $173.87 | $289K |